Helix Immersion Programme Partners

About Allozymes

Allozymes consists of a team of scientists, creators, and innovators unlocking the power of biology to create a more sustainable future. Our advanced enzyme discovery and engineering platform is transforming the world of biosolutions across diverse industries.

Job Description

This role involves overseeing customer projects, managing existing accounts and internal developments within Allozymes, ensuring they are completed on time, within scope, and within budget.

Roles and Responsibilities

• Work closely with the Chief Technical Officer to ensure successful delivery of project outputs to schedule and within budgets.
• Overseeing customer projects and internal developments within an organisation, from the start through to completion 
• Developing project scopes and objectives, involving all relevant stakeholders and ensuring technical feasibility
• Ensure resource availability and allocation for each project
• Formulate, organise and monitor inter-connected project
• Coordinate cross-project activities
• Develop detailed work breakdown structures and project plans to ensure delivery of agreed outcomes 
• Perform risk management to minimise project risks
• Create and maintain comprehensive project documentation
• Serve as the point of contact, to enhance collaboration between the business team and R&D team and ensuring timely execution of project
• Oversee project progress, addressing any issues with a focus on aligning Allozymes deliverables to the customers

Requirement of Qualifications, Skills and Experience

• Fresh PhD/Master’s in Science with commercial experience within the life science sector.
• Flexible approach to work assignments, ability to manage multiple and varied tasks and to prioritise the workload whilst maintaining attention to details
• Excellent interpersonal skills, verbal and written communication skills aligned with the ability to build and maintain strong relationships at sites and with service providers.
• >1 year working knowledge of program/project management preferred 
• Outstanding leadership and organisational skills

About Axcynsis Therapeutics

Axcynsis Therapeutics is a platform-based biotechnology company focusing on the development of Antibody-X Conjugate (AXC) therapies to revolutionise cancer treatments. Leveraging on proprietary technologies, we are developing a robust pipeline of AXC candidates with the potential to address unmet medical needs for new treatment options.

Roles and Responsibilities

• Lead and coordinate cross-functional teams to ensure timely and on-budget delivery of trial milestones.
• Prepare, review, and maintain essential clinical trial documents (Investigator Brochure, Protocol, ICFs, and Trial Master File).
• Manage the IRB/EC approval process across all trial sites.
• Lead clinical budget planning, contract negotiations, and financial oversight of CROs, vendors, and sites.
• Oversee selection, qualification, and ongoing performance of clinical vendors and investigative sites.
• Coordinate Investigational Product (IP) labeling, packaging, distribution, and ongoing supply logistics.
• Manage biological sample logistics, ensuring proper handling, shipment, and storage.
• Foster strong working relationships with clinical sites to support protocol compliance and patient recruitment.
• Serve as the central communication point for internal development teams, external partners, and KOLs.

Requirement of Qualifications, Skills and Experience

• PhD in life sciences or a related field;
• Minimum 2 years of clinical project management experience.
• Proven track record in managing early-phase (especially Phase 1) U.S.-based clinical trials.
• Prior experience in oncology trials is essential; ADC experience is a strong advantage.
• Strong vendor and site management capabilities.
• Solid understanding of FDA regulations, IND requirements, and ICH-GCP guidelines.
• Proficient with TMF systems, CTMS, and other relevant clinical trial platforms.
• Excellent leadership, interpersonal, and problem-solving skills.

About Castomize

Castomize is a new med-tech startup that uses proprietary advanced manufacturing methods to create orthopaedic casts that are lighter, stronger, and more comfortable.

Job Description

The biomechanical engineer will further the development of Castomize’s portfolio of medical device products from a biomechanics perspective. The current portfolio of products include orthopaedic casts and prosthetics.

This role is responsible for framing questions, conducting studies, analyzing data, interpreting results, communicating actionable insights, facilitating collaboration between internal product development teams and external problem owners, and prototyping ideas toward commercialisation. 

He/she will mainly be using 3D modelling design software and 3D printing techniques to conduct iterative prototyping and commercialization of products, along with other tasks related to product development and commercialization. 

Roles and Responsibilities

• Use 3D modelling software to design Castomize’s products 
• Keep track of and report on product development progress 
• Use 3D printers, and oversee the 3D-printing process of prototypes to minimize errors 
• Provide inputs and suggestions to enhance the product development process 
• Work closely with the product development team to share knowledge and cross-develop 
• Liaise with external stakeholders regarding product development and production 
• In conducting studies, should have the ability to gather robust biomechanics data while gauging and incorporating subjective feedback, with the agility to adapt research methods 
• Data reduction, analysis, and interpretation 
• Clear, concise, actionable communication of research to designers and cross-functional audiences 
• Ability to zoom in and out -  see the minute detail and big picture concurrently. 

Requirement of Qualifications, Skills and Experience

• Master’s Degree or PhD in related fields 
• Proficiency in 3D modelling and design 
• 3-5 years research experience: musculoskeletal, soft tissue, prosthetic, exoskeleton biomechanics, and sports biomechanics 
• Experience with designing healthcare-related products is a plus 
• A passion for solving problems and providing value-added solutions with attention to detail 

About Digital Life Line

Incorporated in 2021, Digital Life Line is a Singapore-based ISO13485-certified medical technology company that combines clinical expertise, global manufacturing know-how, and regulatory proficiency to rapidly bring to market diagnostics that enables accurate and convenient early screening. 

DLL has a proven track record of working with renowned institutions in Singapore to accelerate the commercialization of best-in-class, highly de-risked breakthroughs through manufacturing, regulatory and market distribution.

Job Description

We are seeking a highly skilled and self-driven developer to join our dynamic team to support our product development efforts. The ideal candidate will have a strong background in python programming and experience using Flask, Docker, HTML5, CSS and pandas. The software development scope will cover key product development milestones, including and not limited to product improvements/upgrades in response to market feedback. The candidate will also be counted on to contribute towards the usability of both software and hardware components to ensure that products can be readily adopted and commercialised in local and overseas markets with underserved community vision screening.

Roles and Responsibilities

• Maintain and update program code as part of software lifecycle management

• Extract and perform basic data analytics from vision screening results

• Create and support online databases for users and backend admin

• Identify bugs and troubleshoot in real-world deployment

Requirement of Qualifications, Skills and Experience

• Master’s / PhD in relevant fields

• Python Programming: Develop high-quality software design and architecture by studying information needs, conferring with users, and studying systems flow, data usage, and work processes. 

• Flask: Utilize Flask to develop web applications and manage the interchange of data between the server and the users. 

• Docker: Use Docker to automate the deployment of applications inside software containers. 

• HTML/CSS: Design and implement attractive and functional websites using HTML and CSS. 

• Pandas: Manipulate, analyse, structure and visualize data using pandas dataframes. 

• Statistical Analysis: Perform statistical analysis using Python libraries to interpret data and make recommendations based on the findings. 

About Hilleman Laboratories 

Hilleman Laboratories was established in 2009 as an equal joint venture between Merck Sharp & Dohme Corp. (MSD), a global research-driven pharmaceutical company and Wellcome Trust, a global charitable foundation dedicated to health. Hilleman Laboratories’ mission is to develop affordable vaccines and biologics against infectious diseases that affect low- and middle-income countries. 

Hilleman Laboratories is establishing a first-of-its-kind vaccine and biologics development and manufacturing hub in Singapore comprising a 30,000 square foot current Good Manufacturing Practices (cGMP) facility and a state-of-the-art research and development facility. 

Job Description 

The incumbent will be involved in day-to-day support in biologics and vaccine manufacturing operation by providing operation/maintenance input and facilitate decision making. He/she will act as user representative/area owner in terms of technical transfer of process and product from R&D and CMC to GMP clinical manufacturing of different modalities and platforms to meet tech transfer objectives and timeline. He/she will commission the first-of-its-kind multiproduct cGMP manufacturing suites (mammalian and microbial) within the project timeline and budget. 

Roles and Responsibilities 

• Responsible for ensuring that the manufacturing activities are performed in accordance with EHS guidelines and in a cGMP-compliant manner. 

• Provide input to operation and equipment in the tech transfer activities of new product/process. 

• Draft, author and/or provide inputs in documentations such as facility fit assessment, user requirements, raw material identification, batch records, SOPs, and process recipes. 

• To coordinate with relevant departments, stakeholders in tracking of operation progression to ensure project milestones are met. 

• Perform and lead root cause analysis for operational related deviations and investigations using established problem-solving tools. 

• Train and coach manufacturing team in process and equipment knowledge to ensure operations are conducted in a safe manner. 

• Manage change controls and deviations of GMP runs for clinical manufacturing. 

• Support process/equipment qualification/validation activities and studies. 

• Front auditors during regulatory audits as the SMEs of the department. 

• Perform cleaning of equipment and cleanrooms as and when necessary. 

Requirement of Qualifications, Skills and Experience 

• Master’s degree in an engineering/scientific discipline (Bio/chemical engineering/life science/biology/chemistry), with 2-6 years relevant industry experience. 

• Plant start-up or commissioning and/or operational experience in biologics and/or vaccines. 

• Experience in biological technology transfer will be an advantage. 

• Experience/knowledge of cGMP practices applicable to upstream/downstream virus manufacturing processes, process development is desirable. 

• Thorough knowledge of Good Documentation Practices (GDP) and Current Good Manufacturing Practices (cGMP). 

• Well-organized and detail-oriented, with ability to effectively prioritize tasks with agility, eager to learn, interact and collaborate effectively with various stakeholders in a team environment and consistently demonstrate reliability and responsibility. 

• Good team player with good working ethics, initiative, diplomacy, positive influencing abilities and drive. 

• Good oral communication and demonstrable, exemplary writing skills. 

• Experience with problem solving and statistical tools will be an advantage. 

About Mesh Bio

Multidimensional Health Intelligence Platform for digital powered care delivery

Mesh Bio is a fast growing digital health startup focused on addressing the growing challenges in care delivery. Mesh Bio develops AI powered clinical decision support, analytics and automation solutions for healthcare providers to transform healthcare delivery with digital solutions. Mesh Bio actively builds an environment for personal excellence and career growth. Encouraging diversity of experiences/backgrounds and want team members to thrive in their domain of professional expertise.

Job Description

As a Digital Twin Product Lead, you will be responsible for driving the success of our novel digital twin SaMD, leading its market launch, achieving product-market fit, expanding its presence globally and responsible for the product’s roadmap. You will play a crucial role in navigating the regulatory landscape, securing product registration in new markets, and driving the FDA approval process in the US, along with obtaining reimbursement. This is a unique opportunity to shape the future of digital health technology and make a tangible impact on global healthcare.

Roles and Responsibility

Launch and Product Market Fit

• Lead the development and execution of a comprehensive go-to-market strategy for our digital twin SaMD, including product positioning, messaging, pricing, and distribution.
• Collaborate closely with the marketing, sales, clinical, and engineering teams to ensure alignment on product goals, timelines, and launch plans.
• Identify key market segments and customer personas to target for early adoption, pilot programs, and strategic partnerships.
• Develop and manage relationships with key opinion leaders (KOLs), healthcare providers, and other stakeholders to drive product awareness, adoption, and endorsement.
• Oversee the creation of sales enablement tools, training programs, and marketing collateral to support the commercial launch.
• Analyse market trends, customer feedback, and competitive landscape to refine product features, value propositions, and overall market strategy.
• Track and report on key performance metrics to measure product-market fit and inform continuous improvement efforts.

Regulatory Strategy and Market Expansion

• Lead product registration and regulatory approval efforts in new markets, such as Indonesia and Malaysia.
• Develop and execute regulatory strategies to ensure compliance with local, regional, and international standards.
• Work with local regulatory consultants, partners, and authorities to navigate regulatory requirements and obtain necessary approvals.
• Collaborate with cross-functional teams to align regulatory strategies with broader business goals and timelines.
• FDA Approval and Reimbursement Lead the FDA approval process for our digital twin software in the US, including developing submission strategies, managing documentation, and liaising with regulatory authorities.
• Work closely with legal and regulatory affairs teams to ensure all regulatory requirements are met and submissions are completed on time.
• Develop and implement strategies to secure reimbursement, including engaging with payers, advocating for coverage, and creating value dossiers and health economic models to demonstrate product benefits and cost-effectiveness.
• Monitor changes in reimbursement policies and regulations, and adjust strategies accordingly to maximise reimbursement opportunities.

Commercialisation and Market Growth

• Develop and manage the product roadmap to align with market needs, business objectives, and regulatory requirements.
• Identify and establish partnerships with healthcare providers, distributors, and other channel partners to expand market reach and drive product adoption.
• Create and execute strategies to support the scaling of the product in new and existing markets, including localisation, training, and support.
• Work with sales teams to set commercial targets, monitor performance, and adjust strategies to meet revenue goals.
• Stay informed on industry trends, competitor activities, and emerging technologies to ensure the product remains competitive and aligned with market demand.
• Any ad-hoc related task as assigned by superior.

Requirement of Qualifications, Skills and Experience

• Min Master’s degree in Life Sciences, Nursing, Biomedical engineering or equivalent
• Proven experience in product management, preferably in the healthtech, medtech, or digital health sectors.
• Strong knowledge of regulatory requirements for software as a medical device (SaMD) in multiple regions, including US FDA, CE Mark, and other relevant jurisdictions.
• Experience in launching digital health products and achieving product-market fit.
• Demonstrated experience in leading product registration and regulatory approval processes in multiple markets.
• Excellent communication, leadership, and project management skills.
• A passion for innovation in healthcare and improving patient outcomes.
• Personality: Self-starter, client-oriented, independent, and able to function in a dynamic start-up environment.

About Mesh Bio

Multidimensional Health Intelligence Platform for digital powered care delivery

Mesh Bio is a fast growing digital health startup focused on addressing the growing challenges in care delivery. Mesh Bio develops AI powered clinical decision support, analytics and automation solutions for healthcare providers to transform healthcare delivery with digital solutions. Mesh Bio actively builds an environment for personal excellence and career growth. Encouraging diversity of experiences/backgrounds and want team members to thrive in their domain of professional expertise.

Job Description

The Product Manager (“Manager”) is a key commercial position that is dedicated to delivering Mesh Bio’s healthcare software solutions to customers and partners. The Manager is expected to work together with other company functions, including the Engineering department, Sales & Customer Success in meeting customers’ needs.

Roles and Responsibility

• Explore and evaluate new opportunities, validate customers, identify new business models and areas where Mesh Bio’s solutions can add significant, differentiated value.
• Lead the customer’s discovery process for new products, helping to unearth customer’s business objectives and current pain points and translate to user requirements specification.
• Ability to wear multiple hats including product, marketing, and business to quickly assess product, technology and business risks, competitive landscape, differentiation, etc.
• Draft up product requirements specifications which matches product features and capability built on users’ requirements.
• Act as a key liaison between Product, Sales, and Engineering, funnelling customer feedback to help shape the product roadmap.
• Assist in conducting competitive analyses and preparing go-to-market plans for new products, including early-stage needs finding, user research, market analysis.
• Work closely with the Product Designer and the Engineering teams to build prototypes, test, and iterate.
• Conduct Proof-of-Concepts/Pilots where necessary to help customers validate technical requirements.
• Assist in delivering value-based demonstrations highlighting our platform’s ecosystem
• Lead and manage the implementation of product new features, along with the Engineering department.
• Serves as Technical Lead for Healthcare Solution Engineers and Customer Success Specialists and managing their tech related issues and communications with Engineering
• Assist in managing the implementation and onboarding of new customers
• Assist in managing the product vision and product roadmap
• Serves as a key liaison within the commercial department in meeting the needs of ISO27001 and ISO13485
• Contribute to the success of a rapidly changing and growing organization
• Some regional travel may be required subject to visa requirements.
• Any ad hoc work related tasks as assigned by Superior. 

Requirement of Qualifications, Skills and Experience

• Minimum Masters degree in Life Sciences, Nursing, Biomedical engineering or equivalent
• 3 - 5 years prior experience working with an early-stage proprietary product in a life science, healthcare, or medical device setting 
• Comfortable and confident of speaking to doctors and healthcare workers
• Comfortable with collaboration, open communication and reaching across functional borders
• Ability to multi-task and manage tasks with varying priorities
• Personality: Self-starter, client-oriented, independent, and able to function in a dynamic start-up environment.

About Mirxes

An RNA technology company that develops and commercialises accurate, non-invasive, and affordable blood-based miRNA test kit products for the early detection of cancer and other diseases.

Roles and Responsibilities

• Deriving QA and QC guidelines pertaining to NGS data for in-house NGS workflows.
• Develop novel algorithms for genome assembly, variant detection (SNPs and InDels) and structural variant detection (CNVs, Inversions and Translocations) for a clinical-grade genome analysis.
• Setting up bioinformatics pipelines that are compliant to MOH and CAP standards.
• Lead development work to maintain and improve distributed workflow management infrastructure, LIMS, and other critical infrastructure.
• Supporting data analysis and troubleshooting during analytical validation and during routine operation.
• Writing the SOPs for bioinformatics pipelines and oversee the day to day running of the pipeline workflows.
• Support the patient results reporting process. Ability to extract SNVs, CNVs, indels and gene fusions from NGS data. Analyze clinical datasets to generate clinical diagnostic reports.
• Routine maintenance of the sequence data, including backup and storage of the clinical data.
• Identify and correct any weaknesses in systems or team processes related to security, completeness and quality of data analysis, efficient resource usage, or robustness.
• Perform other related duties as assigned.

Minimum Qualifications

• PhD or MSc in Bioinformatics or relevant industries
• Experience in leading algorithms/software development projects and teams.
• Strong experience developing bioinformatics algorithms and tools used in NGS analysis as evidenced by publications and GitHub repositories.
• Clinical experience or experience in clinical research, in cancer NGS/genomics would be highly desirable
• Experience developing Machine Learning algorithms is a plus.
• Experience in automating management of distributed systems in the Cloud, including provisioning, administering, testing, and monitoring.
• Experience with REST API design.
• Strong team player with positive work attitude, analytical minded, result-oriented, good communication and interpersonal skills

About Mirxes 

Mirxes is an RNA technology company that develops and commercialises accurate, non-invasive, and affordable blood-based miRNA test kit products for the early detection of cancer and other diseases. 

Job Description 

The Genomics lab is looking for a Research Scientist, whose focus is to develop NGS workflow for academic and clinical research service, and train technical personnel, leading to the implementation of these new workflow in a commercial service lab environment. The appointment holder is expected to have an advanced degree with working experience in NGS technologies. The ideal candidate would be well-balanced between having the discipline to work in a commercial service laboratory environment, and a passion for translating innovative, newly developed laboratory tests for commercial implementation. 

Roles and Responsibilities 

• Lead the molecular assay development and validation efforts in a commercial service lab setting. 

• Demonstrate hand-on leadership to successfully implement NGS service workflow in the commercial service laboratory. 

• Design, plan and execute validation tests, establish QC criteria, write validation plan and report. 

• Lead the SOP writing and technology transfer to the operations team 

• Propose and implement process improvements and EQA 

• Work closely with other Scientists and Product Managers to provide scientific inputs related to company products and testing services. 

• Support other commercial activities as required. 

Minimum Qualifications 

• PhD. in related Science background with 1 – 2 years’ experience in molecular biology or related field 

• MSc. in related Science background with 3 – 5 years’ experience in molecular biology or related field 

• Demonstrated independent research & development work in a molecular biology lab setting 

• Strong understanding and working experience on NGS technologies is highly desirable. 

• Experience in developing and implementing new molecular assays in a commercial service laboratory is an added advantage. 

• Experience in single cell sequencing will be an added advantage. 

• Be a ‘hands-on’ person who welcomes challenges, works independently or as part of a team, and can communicate effectively at all levels 

About NousQ

NousQ is a new medtech startup company that develops a surgical medical device in the Ear, Nose and Throat (ENT) field to address a key unmet healthcare need in glue ear treatment. It offers a novel solution by providing the world's first automated device that could revolutionise the current way of treating the condition. 

NousQ is proud to be the Top 5 winners of the Medtronic APAC Innovation Challenge 2022, and is honoured to be the winner of other innovation challenge such as MedTech Innovator Challenge APAC 2022 Accelerator Cohort, Victoria Health Week MedTech Festival as well as the recent China TusStar APAC Challenge. 

https://www.nousq.com/ 

Job Description

NousQ is a Singapore-based company focusing on research, design, develop, manufacture and commercialize medical technology and solutions that optimize healthcare delivery and serve large unmet needs for patients. The focus is on patient-centric solutions that patients really want and need.  Currently, NousQ is looking for a passionate firmware engineer to join our growing team.   

We want to introduce the world to CLiKX, a revolutionary and cutting-edge robotic medical device. CLiKX will transform glue ear surgeries by moving the procedure from the operating room to an outpatient setting. As a result, the time, money, and resources needed for such a procedure are significantly reduced.  

You will join our team of pioneer innovators in bringing CLiKX to the millions of untreated children who suffer from glue ears. 

Roles and Responsibilities

• Participate in ideation, conceptualization, design and iteration, verification and validation, manufacturing support for new product pipeline involving embedded system. 

• Be involved in design reviews to identify issues and derive robust solutions that meet the intended use, safety and effectiveness, as well as quality of the product. 

• Collaborate with manufacturing partners to communicate design concepts, technical and/or business trade-offs, and engineering solutions. 

• Perform firmware engineering tasks including:
  (1) Translate/refine high-level requirements into the architecture and engineering specifications of the firmware system;
  (2) Design, develop, integrate and debug/troubleshoot the embedded system/MCU-related hardware to meet the defined objectives, targeted cost and schedule;
  (3) Support the development and execution of relevant test plans, including unit test, integration test and system test to verify and validate that the product can meet all requirements;
  (4) Support functional and reliability tests to ensure safety and performance of the overall product systems. 

• Generate and maintain the necessary documentation for the firmware systems, including design documents, firmware architecture, schematics, SOP/work instructions, Device Master Record (DMR) and other documentations needed to meet the regulatory requirements such as Design History File (DHF), IEC62304, ISO13485 & FDA 21 CFR Part 820. 

• Oversee firmware design change orders and support any relevant verification and validation activities. 

• Support ad-hoc administrative duties as and when required to ensure smooth operation of the company’s activities. 

Requirement of Qualifications, Skills and Experience

• Master’s/PhD degree in Biomedical/Electronics/Computer Engineering with experience in embedded system development. The engineer will be a part of the startup team focusing on product realisation process. 

• Good understanding of product realisation process and preferably with prior experience or interest in embedded system design and development processes. 

• Relevant experiences include coding with programming language such as C/C++ and/or competent in applying other similar IDEs/toolchains for firmware development. 

• Knowledgeable in quality concepts including verification and validation, and reliability testing. 

• Good understanding of medical device software regulatory requirements, such as IEC62304 and/or FDA Software in Medical Device requirements. 

• Excellent communication skills in spoken and written English and good inter-personal skills to engage and interact with team members, vendors, consultant and any potential third party. 

• Possess a high level of integrity, independent, self-motivated and enjoy working in a fast-paced startup environment. 

• Experience in electronic circuit design and/or AI/ML-related development is a plus. 

Skills to be learnt

• Electronics 

• Printed Circuit Board (PCB) Design 

• Product Development 

• Product Management 

• Usability Design 

• Hardware Design 

This project is in partnership with Trinity Innovation Bioventure Singapore (TIBS) and National Health Innovation Centre Singapore (NHIC). 

About Trinity Innovation Bioventure Singapore

Trinity Innovation Bioventure Singapore (TIBS) is a licensed biomed venture capital fund focusing on innovation and value investment with deep insight and experience on Asia markets. The team is led by industrial veterans who have managed multiple VC funds and invested in over dozens of biotech companies. 

Job Description 

TIBS is seeking an entrepreneurial Venture Building Lead to support the incubation and growth of early-stage biotech companies in Singapore. The Venture Building Lead will work closely with scientific researchers, entrepreneurs, investors, and other stakeholders to transform scientific breakthroughs into globally competitive biotech companies. This role requires a combination of drug discovery knowledge and business skills to support early-stage companies in building a strong foundation for growth. 

Roles and Responsibilities

• Lead the venture building projects and support the collaborations with research institutes in Singapore.

• Source investment opportunities to translate scientific breakthroughs into a corporate venture. 

• Lead or support new venture building including research plan, budget forecast, market landscape analysis, team recruiting and risk control plan. 

• Conduct market research to understand the demand, competition, and feasibility of new ventures. 

• Perform research in the scientific field and gather intelligence by establishing the key business drivers, determining the barriers to entry and identifying the key competitors. 

• Support fundraising activities for the incubation projects. 

• Build partnerships with key players in the biotech ecosystem, including research centres, corporate partners, and government agencies. 

• Offer hands-on support to startups in areas like project management, strategic planning, and problem-solving. 

Requirements of Qualifications, Skills and Experience

• Education: Advanced degree in biomedical field (e.g., Biology, Medicine, MD). 

• Experienced with biotech startups, research institutes, or a similar field. 

• Industry Knowledge: Good understanding of drug discovery protocol, and the biotech startup landscape. 

• Financial Skills: Experience with financial modelling and venture financing is a plus. 

• Analytical Skills: Ability to collect, organize, analyze, and disseminate significant amounts of information with attention to detail and accuracy. 

• Others: Good interpersonal skills, and ability to persuade, negotiate and influence 

This project is in partnership with Trinity Innovation Bioventure Singapore (TIBS) and National Health Innovation Centre Singapore (NHIC). 

About Trinity Innovation Bioventure Singapore

Trinity Innovation Bioventure Singapore (TIBS) is a licensed VC fund in Singapore, dedicated to investing on biomedical innovations. As an investor, TIBS supports passionate scientists and entrepreneurs in transforming ground-breaking scientific research into successful corporate ventures. By partnering closely with scientists and entrepreneurs, TIBS aims to advance innovations into novel drugs that address unmet medical needs.

Project Background

TIBS is looking to build new Biotech companies in Singapore for novel drug discovery. One of the projects in the pipeline is to collaborate with local researcher to build a NewCo. of drug discovery and early development for enable scientific innovation to address unmet medical needs. The project has been developed to the stage that we are looking for a full-time project lead to drive the NewCo. set up, and R&D activities from hit to lead, to pre-clinical and early development.

Job Description

TIBS is seeking a highly motivated, self-driven Project Manager to lead and manage early-stage drug discovery projects. This role will drive project execution, manage external partnerships, build internal capabilities, and support the development of business proposals and external partnerships. This role is critical for ensuring the efficient advancement of novel therapies toward preclinical and clinical milestones.

The ideal candidate will ensure projects meet scientific and operational goals, while also contributing to the company's broader strategic growth through business proposal generation and business development support.

This Project Manager will participate in the new company once the NewCo. is set up.

Roles and Responsibilities

Project Management and Execution

• Plan, coordinate, and lead drug discovery.
• Manage project timelines, budgets, risk assessments, and deliverable tracking.
• Ensure achievement of key scientific and operational milestones with high quality standards.

External Partner Oversight

• Manage activities conducted by CROs, academic collaborators, and external partners.
• Oversee chemistry, biology, pharmacology, and preclinical studies to ensure timely and high-quality outcomes.

Internal Capability Development

• Oversee tech transfer to build the internal competency in drug screening and assessment systems.

Scientific and Strategic Oversight

• Collaborate closely with biology, chemistry, translational, and preclinical teams on study design, data interpretation, and decision-making.
• Stay informed on scientific advances related to the project.

Business Proposal and Business Development Support

• Prepare scientific and technical content for business proposals, grant applications, partnering decks, and investor materials.
• Collaborate with the business development and executive team to craft compelling project narratives for external engagements.
• Participate in scientific due diligence discussions, partnering meetings, and represent program updates to potential partners and investors.

Cross-functional Leadership

• Coordinate project research activities between discovery, biology, chemistry, translational science, and preclinical groups.
• Lead project meetings, manage communication flows, and ensure alignment across stakeholders.

Project Reporting

• Deliver high-quality internal reports, milestone updates, board presentations, and partnership briefing documents.

Requirements of Qualifications, Skills and Experience

• Ph.D. or Master’s degree in Biology, Pharmacology, Biochemistry, or a related discipline;
• 5+ years of project leadership experience in biotech or pharmaceutical drug discovery settings. IND enabling experience is preferred
• Hands-on experience managing external research collaborations and internal cross-functional teams;
• Experience with biological assay development, biomarker measurements, or pharmacology research;
• Excellent project management, organizational, and scientific communication skills;
• Ability to synthesize complex scientific information into clear, business-facing deliverables;
• Highly committed to drive the venture building process and demonstrate ability to take critical positions in the NewCo.

Preferred Qualifications

• Experience contributing to partnering discussions, due diligence processes, or strategic business development efforts;
• Prior experience in an early-stage biotech or startup environment;
• PMP certification or equivalent project management training is a plus.

About Vivo Surgical

Vivo Surgical is a patient-focused, clinically-driven medical device developer and manufacturer. Headquartered in Singapore with commercial and co-innovation partnerships spanning multiple international territories, the company is pioneering a novel endoscopic robot for complex endoluminal procedures along the gastrointestinal tract. ISO 13485 certified with international accreditations such as the FDA and CE mark, Vivo Surgical’s proprietary devices target the medical needs of the world through innovative applications of science & technology.

Job Description

We value the importance of having a robust engineering team that would serve as a key pillar for sustained commercial success. To that end, we are looking for an Embedded Software Engineer to join us on this journey. In this role, you will be part of our fast-growing team and will take ownership of your role from the get-go. You will be working on the software development of our robotic system from the design and development phase all the way to manufacturing. Throughout the process, you will be involved in the features development, functional safety enhancements, and supporting the testing phases by developing test specifications and reports.

Roles and Responsibilities

• Assist in the establishment of the system’s design and software requirements according to users’ needs.
• Design and develop Software Architecture and Detailed Design documents based on the requirements.
• Develop and test the software modules following respective standards and best practices.
• Carry out software testing and debugging activities alongside other engineering teams.
• Assist in developing test protocols and reports to verify various subsystems and the main system.
• Take part in code review, change control and risk management documentation generation tasks.
• Work with the team to optimise the system’s cost, manufacturability, quality, and reliability.
• Contribute and watch your ideas materialise into the fast-paced iterations of our system to constantly strive to meet the end users’ needs.

Requirement of Qualifications, Skills and Experience

• Minimum Master's degree in Computer Science / Computer / Electronics Engineering, or related.
• At least 3 years’ experience in Embedded Systems or Firmware Development.
• Proficient in C, C++, Python, Qt framework. Experience in MISRA Compliance adherence will be advantageous.
• Hands-on experience with driver and application layers on ARM MCUs.
• Development of embedded communication protocols such as UART, I2C, SPI, CAN, Ethernet.
• Good knowledge, hands-on experience in RTOS, and familiarity with the Linux environment.
• Experience in Software development on Multicore CPU will be a plus.
• Experience in Functional Safety SDLC will be a plus.
• Understanding standards such as IEC 62304, IEC61508 & EN50128 will be a plus.

About Xenolis

Xenolis Pte Ltd is a platform-based life sciences company focusing on the development of synthetic aptamers. Leveraging on our unique technologies, we are developing DNA and RNA-based solutions in their field of use. We are currently seeking motivated Research Scientists to join our R&D team in Singapore.

Roles and Responsibilities

• Generate and characterise nucleic acid aptamers
• Develop a new biotechnology based on genetic alphabet expansion
• Perform a variety of assays (e.g. cell signalling bioassay, internalisation/trafficking assay, protein-based and cell-based binding assays) and immunological-related assays (e.g. ELISA, flow cytometry)
• Perform mammalian cell culture experiments and maintenance
• Maintain detailed documentation of research, protocols, SOPs, inventories, maintenance logs, etc
• Take on laboratory management duties including but not limited to procurement, inventory management, laboratory equipment maintenance
• Ensure compliance with standard operation procedures, in-house safety measures and other industry practices

Requirement of Qualifications, Skills and Experience

• Knowledge of basic chemistry/biology and molecular biology, including nucleic acid research
• PhD, a Master degree, or a Bachelor degree in a Life Science, Biological Science, Biochemistry or related disciplines
• Wet lab experience with chemistry and biology for nucleic acids and proteins
• Proficient with high-dimensional data analysis, and familiar with the use of genomic analysis, computational biology, statistical and visualisation tools
• Experienced in cell culture and molecular lab techniques
• Excellent organisational skills
• Excellent interpersonal and verbal/written communication skills
• Self-motivated with a proactive attitude
• Strong troubleshooting and problem-solving skills
• Ability to work independently and collaboratively with team members in a fast-paced biotech startup