About BioChromatographix

BioChromatographix is a startup company developing novel chromatography media for purification of viruses and other biological materials.

Main objectives and responsibilities

We seek a Scientist with hands-on laboratory experience in development and manufacturing at our Singapore laboratory, reporting to the Director of Technical Development and Manufacturing. The Scientist will be responsible for producing various biotherapeutics using aseptic cell culture techniques, followed by screening and evaluation of purification methods using various chromatography columns. Assays will be performed to quantify the performance of the purification processes.

Task and duties

Technical development:

• Design experiments and prepare protocols.
• Conduct experiments to evaluate and characterize chromatography media.
• Perform analysis of samples.
• Maintain laboratory equipment and manage inventory.
• Prepare technical reports, document experimental results and create presentations.

Manufacturing:

• Establish and execute manufacturing operations.
• Work with external experts to optimize manufacturing workflows and process parameters.
• Ensure manufacturing is performed on time to meet production schedules as set by marketing.
• Manage development and production of chromatography columns.
• Collaborate with Quality Control and Quality Assurance functions.

Support client applications:

• Collaborate with marketing team and participate in client meetings.
• Conducting application studies, including drafting protocols and reports.
• Write application notes and white papers.

Other technical work related assignments may be required.

Requirements

• PhD in Chemical Engineering, Molecular Biology, Biochemistry, or a related field.
• Minimum of 2-4 years experience in cell culture, protein purification and bioassay testing.
• Experience in the following analysis techniques:
• qPCR, ELISA, flow cytometry
• SDS-PAGE and Western Blot
• Prepare and analyze data using statistical software, e.g. Excel, GraphPad Prism.
• Strong written and verbal communication skills.
• Excellent organisational skills and attention to detail.
• Ability to work collaboratively in a team-oriented environment.