Allay’s first product, ATX-101, is currently undergoing a global clinical trial for use in Total Knee Replacement surgery. It is designed to provide the weeks of pain management required for a successful transition into post-surgical rehabilitation, reducing the need for constant re-dosing, clinical oversight and avoiding the drawbacks of systemic analgesics such as opioids.

As part of the pipeline development, ATX10X project is focusing on providing pain relief to patients over a different duration for different clinical needs in comparison to our current pain relief investigational products (ATX101) which is currently undergoing clinical trials for Total Knee Replacement (TKR) surgery. As an intern under the programme, the incumbent will be assisting the R&D engineer/chemist in analytical test method development for the pipeline project and any analytical-related testing using various equipment such as High-Performance Liquid Chromatography (HPLC), Gas Permeation Chromatography (GPC), UV-VIS Spectrometer, and Scanning Electron Microscopy (SEM).

The following are examples of the expected job scope:

•    Work on the tunability of the drug release rate

•    To improve on the new manufacturing method used to manufacture the product while still providing the controlled release of the drug over a certain duration.

•    To alter the structural integrity of the product using different excipient

•    To find an alternate biodegradable polymer that has a faster resorption rate.

•    To explore the use of different API